Oxytetracycline Hydrochloride
CAS: 2058-46-0
MF: C22H25ClN2O9
MW: 496.89
EINECS: 218-161-2
Chemical Properties Yellow Crystalline Solid
Usage Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial
Description:
Oxytetracycline hydrochloride is a salt prepared from oxytetracycline taking advantage of the basic dimethylamino group which protonates readily to form the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, oxytetracycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
DESCRIPTION | YELLOW CRYSTALLIN POWDER | COMPIIES |
IDENTIFICATION: | ACCORDING TO BP2001 | COMPIIES |
PH VALUE | 2.3 ~ 2.9 | 2.50 |
SPECIFIC OPTICAL ROTATION | -188°~-200° | -188° |
ABSORBANCE (353nm, PH2.0) | 270 ~290 | 275.0 |
LIGHT ABSORBING IMPURITY | ABSORBANCE AT 430nm, <0.50 | 0.32 |
ABSORBANCE AT 490nm, <0.20 | 0.11 | |
RELATED SUBSTANCES | CONTENT OF IMPURITY PEAK MEET THE REQUIREMENTS | COMPLIES |
HEAVY METALS | ≤50<o:p> A(0.2%, 1CM, 430NM)<0.50 | 0.28 |
SULPHATED ASH | ≤0.5% | 0.08% |
WATER | ≤2.0% | 1.3% |
HPLC ASSAY< | 95.0%~102.0% ANHYDROUS SUBSTANCE | 99.5% |

Usage
1. Common hydrochloride as a yellow crystalline powder, odorless, bitter taste; Cited moist; Deep when exposed to light color gradient, failure is easily damaged in an alkaline solution. Soluble in water, slightly soluble in ethanol, insoluble in chloroform or ether.
2. Antibacterial, breathing disease, the pig lung disease, dysentery for the prevention and treatment of Pasteurella multocida, brucellosis, anthrax, E. Coli and Salmonella infections, acute respiratory infections, swine mycoplasma pneumonia. Urinary tract infections caused by susceptible strains, with the clothes vitamin C acidification of the urine. Fairly frequently as feed additives, can prevent the disease, can also improve feed utilization and growth.
Oxytetracycline hydrochloride is a salt prepared from oxytetracycline taking advantage of the basic dimethylamino group which protonates readily to form the salt in hydrochloric acid solutions. The hydrochloride is the preferred formulation for pharmaceutical applications. Like all tetracyclines, oxytetracycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
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